Abstract

Clear cell squamous cell carcinoma (SCC) is a rare variant of SCC of skin in which ultraviolet radiation has been suggested as possible etiology. We report a case of a 51-year-old male patient who presented with a 4 months history of a non-healing ulcer on the left side of his face. Histopathology and immunohistochemistry studies showed Clear cell variant of squamous cell carcinoma. This case showed an aggressive and bizarre clinical presentation but more report of cases are needed to have a better characterization of the clinical presentation and prognosis of this variant of this squamous cell carcinoma variant.

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