Clear cell carcinoma arising from sigmoidal subserosal endometriosis

Abstract

We present an unusual case of clear cell carcinoma arising from endometriosis in a 43-year-old woman. During laparotomy, a right adnexal tumor was found to be a sigmoidal subserosal tumor. Concomitant abnormal findings were endometriosis externa and enlarged ovaries. Intraoperative cytology suggested an adenocarcinoma; however, because of the unusual nature of the tumor and because the patient had not been fully informed about colostomy, further surgery was postponed. During the postoperative follow-up, the tumor grew and repeat aspiration cytology also suggested an adenocarcinoma. The patient again underwent laparotomy, and a Miles operation, total abdominal hysterectomy, bilateral salpingo-oophorectomy, regional lymphadenectomy and descending colostomy were performed.