Abstract
Endometriosis is a frequent benign disorder. Malignancy arising in extraovarian endometriosis is a rare event. A 49-year-old woman is presented with a large painful abdominal wall mass. She underwent a myomectomy, 20 years before, for uterus leiomyoma. Computed tomography suggested that this was a desmoid tumor and she underwent surgery. Histological examination showed a clear cell adenocarcinoma associated with endometriosis foci. Pelvic ultrasound, computed tomography, and endometrial curettage did not show any malignancy or endometriosis in the uterus and ovaries. Adjuvant chemotherapy was recommended, but the patient was lost to follow up. Six months later, she returned with a recurrence of the abdominal wall mass. She was given chemotherapy and then she was reoperated.
Highlights
We report a case of clear cell adenocarcinoma derived from pathologically confirmed endometriosis in the abdominal wall
The incidence of abdominal wall endometriomas is of 0.04% among parturients undergoing cesarean section and it is more frequent than endometriosis following conventional gynaecologic surgery [4, 5]
A term first coined by LaGrenade and Silvergerg in 1988 in [8, 13], is rare and is characterized by endometriotic glands with cytological and/or architectural atypia
Summary
Several observations of the coexistence of endometriosis and cancer have been published [1, 2]. Malignancy arising in extraovarian endometriosis is a rare event [1]. We report a case of clear cell adenocarcinoma derived from pathologically confirmed endometriosis in the abdominal wall. We discuss the epidemiological and clinicopathological features of malignancy arising in abdominal wall endometriosis
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