Abstract
In this work, we have designed an efficient and convenient method for the synthesis of novel spiro[indene-2,2'-[1,3,5]oxathiazine]-1,3-diones by the one-pot, three component condensation of tetramethyl guanidine, ninhydrin, and isothiocyanates in water. Easy purification, green reaction conditions, easy performance and good yields are some advantages of this procedure.
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