Abstract

Three novel bromine-containing amides, clathrynamides A ( 1), B ( 2), and C ( 3), were isolated from a marine sponge Clathria sp. Their structure were determined on the basis of spectroscopic data. Clathrynamide A ( 1) significantly inhibited cell division of fertilized starfish eggs and also showed inhibition of the growth of human myeloid K-562 cells in vitro.

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