Abstract

As a non-invasive diagnostic tool, Magnetic Resonance Imaging (MRI) has been widely used in the field of brain imaging. The classification of MRI brain image conditions poses challenges both technically and clinically, as MRI is primarily used for soft tissue anatomy and can generate large amounts of detailed information about the brain conditions of a subject. To classify benign and malignant MRI brain images, we propose a new method. Discrete wavelet transform (DWT) is used to extract wavelet coefficients from MRI images. Then, Tsallis entropy with DNA genetic algorithm (DNA-GA) optimization parameters (called DNAGA-TE) was used to obtain entropy characteristics from DWT coefficients. At last, DNA-GA optimized support vector machine (called DNAGA-KSVM) with radial basis function (RBF) kernel, is applied as a classifier. In our experimental procedure, we use two kinds of images to validate the availability and effectiveness of the algorithm. One kind of data is the Simulated Brain Database and another kind of image is real MRI images which downloaded from Harvard Medical School website. Experimental results demonstrate that our method (DNAGA-TE+KSVM) obtained better classification accuracy.

Highlights

  • Human brain image segmentation, as a branch of medical image segmentation, can help us diagnose the diseases of the human brain

  • Since Magnetic Resonance Imaging (MRI) is primarily used for soft tissue anatomy and can generate large amounts of detailed information about the brain conditions of a subject, the use of MRI images to classify normal and pathological brain conditions is very important in clinical diagnosis [2]

  • DNA genetic algorithm (DNA-Genetic algorithms (GA)) is an effective method for this problem compared to the random selection method

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Summary

Introduction

As a branch of medical image segmentation, can help us diagnose the diseases of the human brain. High quality MRI images have been routinely used for obtaining the anatomical and pathological conditions of the brain in both biomedical research and clinical diagnosis [1]. Since MRI is primarily used for soft tissue anatomy and can generate large amounts of detailed information about the brain conditions of a subject, the use of MRI images to classify normal and pathological brain conditions is very important in clinical diagnosis [2]. WT allows for the analysis of images at different resolution levels because they have multi-resolution analysis features. This technology requires a large amount of storage and is computationally intensive [3]

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