Abstract

Intervertebral disc disease (IVDD) has been recognized in dogs since the 1800s, when the first descriptions of extruded disc material within the vertebral canal were published. In the intervening time our understanding of intervertebral disc pathology in dogs and cats has increased dramatically, with many variations of IVDD described. Whilst the volume of literature and collective understanding of IVDD has expanded, there has also been scope for confusion as the definition of intervertebral disc disease, with its myriad different manifestations, becomes more complicated. A large volume of literature has aimed to combine the use of histopathology, diagnostic imaging and clinical findings to better understand the various ways in which IVDD can be classified. Much of this research has focused on the classification of mechanisms of intervertebral disc degeneration, centering around the differences between, and overlaps in, IVDD in chondrodystrophic and non-chondrodystrophic dog breeds. However, with the increasing availability of advanced imaging modalities allowing more accurate antemortem diagnosis, the concept of IVDD has expanded to include other clinical presentations that may not fit into traditional models of classification of IVDD. This review aims to provide an up to date overview of both historical and current systems of IVDD classification, highlighting the important findings and controversies underpinning them.

Highlights

  • Intervertebral disc disease (IVDD) is a broad term that is widely used in veterinary medicine and encompasses a range of lesions affecting the intervertebral disc (Table 1)

  • Given the introduction of several new conditions related to the IVD to the veterinary literature in recent years, we have aimed to evaluate current systems of classification and terminology used to ensure consistent recording of IVDD types

  • The rapidly expanding language used surrounding types of IVDD in the veterinary literature suggests that a consensus on terminology and classification is required to cover multiple types of IVDD, including those falling outside of the traditional Hansen Type I and II system

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Summary

Introduction

Intervertebral disc disease (IVDD) is a broad term that is widely used in veterinary medicine and encompasses a range of lesions affecting the intervertebral disc (Table 1). Initial reports described the presence of cartilaginous material within the epidural space of the vertebral canal (so-called enchondrosis intervertebralis), which was subsequently found to be associated with degenerated nucleus pulposus (1, 3) Building on these findings in the 1940s and 50s, Hansen and Olsson made huge advances in understanding the nature of canine IVDD, proposing a system of classification based on histopathological degenerative changes that persists today (2, 4–7). They described two distinct types of IVD degeneration, namely chondroid and fibroid metaplasia, associated with specific breed and signalment signatures.

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