Abstract
The histologic classification of gliomas, which is based on oligodendroglial- or astrocytic-like morphology distinguishes gliomas in astrocytic tumors (grade 1- pilocytic astrocytoma to grade 4- glioblastoma), oligodendroglial and mixed tumors (grade 2 and 3) according to cell differenciation, cellularity, nuclear atypia, mitotic activity, necrosis and microvascular proliferation. Prognosis is correlated to grade. Based on interobserver variability, the histological diagnosis is often highly subjective and should be interpreted within the context of clinical and radiological data. Newly identified good prognostic markers (1p and 19q loss in oligodendrogliomas) and new molecular techniques such as microarray may further refine the existing classification.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
