Abstract

Background: Reed-Sternberg (HRS) cells of classical Hodgkin lymphoma (CHL) are of B-cell origin. In a small number of CHL cases, the tumor cells can express T-cell antigens (TCA), most commonly CD2 and CD4. But CD8 expression in this setting is extremely rare. One study showed that aberrant TCA expression in CHL is associated with decreased event-free …

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