Clasificación de gravedad y variables de influencia del síndrome poscuidado intensivo

Abstract

ObjectiveThe study aims to characterize postintensive care syndrome by classifying the severity of the disease and identifying the variables of influence in 2 highly complex intensive care units for adults in Colombia. MethodA descriptive, cross-sectional, prospective study was carried out to characterize survivors of critical illness using the Healthy Aging Brain Care–Monitor in a sample of 135 patients. Postintensive care syndrome severity was classified using Gaussian mixture models for clustering, and the most influencing variables were identified through ordinal logistic regression. ResultsClustering based on Gaussian mixture models allowed the classification of postintensive care syndrome severity into mild, moderate, and severe classes, with an Akaike information criterion of 308 and an area under the curve of 0.80, which indicates a good fit; thus, the mild class was characterized by a score on the HABC-M Total scale≤9; the moderate class for a HABC-M Total score≥10 and≤42 and the severe class for a HABC-M Total score≥43. Regarding the most influencing variables, the probability of belonging to the moderate or severe classes was related to male sex (91%), APACHE II score (22.5%), age (13%), intensive care units days of stay (10.6%), the use of sedation, analgesia and neuromuscular blockers. ConclusionIntensive care units survivors were characterized using the HABC-M scale, which made it possible to classify postintensive care syndrome through Gaussian mixture models clustering into mild, moderate, and severe, and to identify variables that had the major influence on the presentation of postintensive care syndrome.