Abstract
In the crystal structure of the title compound, clarithromycin (CAM) monohydrate, C38H69NO13·H2O, the water molecule behaves as a proton donor and is hydrogen bonded to the hydroxy O atom of the CAM cladinose ring. The hydroxy O atom also behaves as a proton donor, forming an intermolecular hydrogen bond with one of the hydroxy groups of the 14-membered aglycone ring. The CAM molecules are linked through these hydrogen bonds into chains running parallel to the c axis.
Highlights
Background functionLegendre polynomialsFractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å2) O1 C1 O2 C2 O3 C3 O4 C4 O5
In the crystal structure of the title compound, clarithromycin (CAM) monohydrate, C38H69NO13H2O, the water molecule behaves as a proton donor and is hydrogen bonded to the hydroxy O atom of the CAM cladinose ring
The CAM molecules are linked through these hydrogen bonds into chains running parallel to the c axis
Summary
Miurab and Shigeru Itaia a Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan, and bIndustrial Application Division, Japan. Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo-gun, Hyogo 679-5198, Japan
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
