Abstract

Clear cell acanthoma was portrayed primarily by Degos [1]. Clear cell acanthoma is also referred to as Degos’ acanthoma or pale cell acanthoma and is cogitated as an asymptomatic, benign epidermal tumor devoid of gender predilection.

Highlights

  • Clear cell acanthoma was portrayed primarily by Degos [1]

  • Clear cell acanthoma depicts uniform, pale keratinocytes or pale epithelial cells with abundant cytoplasm composed of excessive glycogen, centric nuclei and distinct foci of transformation

  • Clinical segregation is required from dermatofibroma, pyogenic granuloma, irritated seborrheic keratosis, keratoacanthoma, actinic keratosis, plaque psoriasis, eccrine poroma, viral warts or malignant cutaneous tumors such as basal cell carcinoma, squamous cell carcinoma, malignant melanoma and metastatic cancer

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Summary

Introduction

Clear cell acanthoma was portrayed primarily by Degos [1]. Clear cell acanthoma is referred to as Degos’ acanthoma or pale cell acanthoma and is cogitated as an asymptomatic, benign epidermal tumor devoid of gender predilection. Clear cell acanthoma or Degos’ acanthoma or pale cell acanthoma is an exceptional, asymptomatic, cutaneous benign tumefaction of obscure etiology, emerging from epidermal keratinocytes. Clear cell acanthoma exhibits a “stuck on” appearance akin to seborrheic keratosis, “vascular countenance” of pyogenic granuloma, “scaling and exudation” elucidated in eczematous reactions and a “progressive margin “associated with an epithelioma.

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