Abstract
Three new polyketides, named cladosporitides A–C (1–3), were isolated from an endophytic fungi Cladosporium tenuissimum derived from the stem of Berberis heteropoda. Their structures were determined by extensive spectroscopic analysis including HRMS, 1D and 2D NMR data. Compound 1 possesses an unusual octahydro-2H-2,5-epoxychromene tricyclic structure moiety. An anti-inflammatory assay indicated that compounds 1–3 showed moderate inhibitory activities against LPS-induced NO production in RAW 264.7 cells with IC50 values ranging from 22.32 to 33.97 μM.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
