Abstract
A formylated triterpene named cladocalol has been isolated from the leaves of Eucalyptus cladocalyx, together with ursulolactone acetate, ursolic acid, 3β-acetate-12,20(29)-lupadien-28-oic acid, β-sitosterol and the known flavonoid eucalyptine. Their structures were mainly established by extensive NMR studies ( 1H NMR, 13C NMR, DEPT, 1H– 1H COSY, HSQC, HMBC) and mass spectroscopy as well as by X-ray crystallographic analysis. In this paper, we report on the cytotoxic effect induced by cladocalol and its derivatives on the myeloid leukemia cell line HL-60.
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