Abstract
Titania nanotube arrays (TNA) nanosystem has been discussed widely in drug delivery applications that could provide advantages for sustaining chemo drug release in targeted cancer therapy. This study profiled the cisplatin chemo drug (CDDP) encapsulation efficiency on TNA (CDDP–TNA). Anatase TNA nanosystem used in this study present with diffraction angle 25 θ and 48 θ. The distribution and binding interaction of CDDP on TNA were identified using the primary functional marker amide I band (N–H), and the sustained release profile of CDDP from TNA was further captured. Furthermore, CDDP–TNA nanosystem is present with favorable hydrophilic properties that could facilitate the effective release of CDDP from TNA nanosystem. However, developing a controlled release model of CDDP -TNA nanosystem using polymer coating technology is needed to support the present finding, especially in targeted cancer therapy applications.
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