Abstract
We present a novel circumferential-scan endoscopic optical coherence tomography (OCT) probe by using a circular array of six electrothermal microelectromechanical (MEMS) mirrors and six C-lenses. The MEMS mirrors have a 0.5 mm × 0.5 mm mirror plate and a chip size of 1.5 mm × 1.3 mm. Each MEMS mirror can scan up to 45° at a voltage of less than 12 V. Six of those mirrors have been successfully packaged to a probe head; full circumferential scans have been demonstrated. Furthermore, each scan unit is composed of a MEMS mirror and a C-lens and the six scan units can be designed with different focal lengths to adapt for lesions with uneven surfaces. Configured with a swept source OCT system, this MEMS array-based circumferential scanning probe has been applied to image a swine's small intestine wrapped on a 20 mm-diameter glass tube. The OCT imaging result shows that this new MEMS endoscopic OCT has promising applications in large tubular organs.
Highlights
Endoscopic optical coherence tomography (OCT) has been drawing a great deal of attention in the optical imaging research community due to its enormous promise in noninvasive early cancer diagnosis and real-time imaging guided tumor removal [1]
Circumferential scanning was first developed for intravascular OCT [10], and it is widely used in clinic [11]
We propose to use a C-lens and a MEMS mirror to compose a scan unit, and six scan units are circular arrayed to be a circumferential scanning probe
Summary
Endoscopic optical coherence tomography (OCT) has been drawing a great deal of attention in the optical imaging research community due to its enormous promise in noninvasive early cancer diagnosis and real-time imaging guided tumor removal [1]. Circumferential scanning was first developed for intravascular OCT [10], and it is widely used in clinic [11] In such a circumferential scanning mechanism, a fiber-GRIN lensprism module is spun through a guide wire driven by an external motor [12,13,14]. The spinning guide-wire type of circumferential scanning probes has been utilized in endoscopic OCT for imaging hollow organs with large lumina, such as esophagus and colon [18,19]. This technology is very efficient to acquire circumferential images, but it has difficulty to image a localized specific region of interest. The focus length of the C-lens is designed at 12 mm in order to image large tubular organs
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