Abstract
Platelet-derived microparticles (PDMP) are first observed as vesicles released from platelets after adhesion to vessels walls.1–3 Circulating PDMP can therefore be thought of as a marker of in vivo platelet activity.4 In these studies, flow-cytometory was applied to measure PDMP. As a result, the clinical significance of PDMP remains unresolved. In this study, we investigate the usefulness of PDMP that could vary the vulnerability for thrombotic events using newly developed ELISA kit.5 Our population consisted of 66 ACS patients with or without ST segment elevation (the ACS group) and 126 patients with stable angina (the SAP group). A further 26 noncardiac chest-pain syndrome patients were selected as a control group. Circulating PDMP levels were assayed using the ELISA method5 (supplement I, available online at http://atvb.ahajournals.org). …
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