Circulating omentin in people with different body mass as an indicator of metabolic risk

Abstract

The aim of the work is to estimate the level of circulatory omentin in Kharkov citizens – representatives of the Ukrainian population – depending on their body mass index, fat content, degree and topography of fat deposition, insulin level in blood, insulin resistance index of HOMA. Materials and methods. Subjects were divided into four groups: with excessive body weight (n=62); with first degree of obesity (n=59); second degree (n=45); third degree of obesity (n=40). The control group consisted of 44 people with normal body weight. The subjects were examined for the body mass index, waist and hips circumference. Fat body mass was examined by bioelectrical impedance analysis method, levels of circulatory omentin and insulin by ELISA. The HOMA index was also calculated. Results and discussion. Among the subjects with normal and excessive body weight, the levels of circulatory omentin were not statistically different, in contrast to the subjects with 1, 2 and 3 degrees of obesity, who had a statistically significant (p