Abstract
The diagnostic relevance of circulating microRNAs (miRs) in acute myocardial infarction (AMI) is a cutting-edge topic both for research and clinical implications. Advances in molecular biology and technology have initiated considerable interest in nucleotide-based biomarkers. The first AMI biomarkers that appeared on the scene were myoglobin, creatine kinase (CK), its isoenzyme MB (CK-MB) and lactate dehydrogenase isoenzyme 1 (LD-1). Even if they are not specific for cardiac muscle damage, they have been used for years to diagnose AMI in patients with chest pain.
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