Abstract
The aim of the study was to assess the relationships between maternal insulin and insulin-like growth factor-1 (IGF-1) concentration and food consumption frequency and the birth parameters of the newborn. A total of 157 mother-newborn pairs participated in the study. The study showed that more frequent consumption of sweet and salty snacks as well as fruit and fruit or vegetable juices may promote greater weight gain in pregnancy and higher newborn birth weight. A significantly higher insulin concentration was found among overweight women according to body mass index (BMI), and a significantly lower concentration of IGF-1 was demonstrated among women ≥35 years of age. There was no significant correlation between the concentration of insulin and IGF-1 in the mother’s blood plasma and the birth weight and length of the newborn. A significant relationship was only found between the concentration of IGF-1 in the mother’s blood and the Ponderal index of the newborn. A woman’s eating habits during pregnancy have a significant impact on the mother’s health and on the proper growth and development of the foetus.
Highlights
IntroductionMaternal nutritional status and metabolic factors have a significant effect on foetal growth and development and determine the health of the newborn
Przybylowicz and Anna DanielewiczMaternal nutritional status and metabolic factors have a significant effect on foetal growth and development and determine the health of the newborn
The aim of the study was to assess the relationship between maternal insulin and insulinlike growth factor-1 (IGF-1) concentration as well as food consumption frequency and birth parameters of the newborn
Summary
Maternal nutritional status and metabolic factors have a significant effect on foetal growth and development and determine the health of the newborn. Pregnancy is a period characterized by numerous metabolic adaptation processes, including an increase in insulin and insulin-like growth factor (IGF) concentrations and an increased pancreatic beta-cell response. Insulin and IGF are involved in the regulation of placental and foetal growth and development. The main function of insulin is the regulation and modulation of metabolic processes and transport of nutrients across the placenta, e.g., glucose and fatty acids. Various IGFs (IGF-1 and IGF-2) are involved in increased glucose uptake, amino acid transport across the placenta, and foetal or placental cell proliferation. Insulin resistance in the cells of the woman’s body develops mainly in the second and third trimesters. The increase in insulin concentration and insulin resistance in pregnancy is a biological mechanism
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
