Abstract
Mast cells (MCs) in peripheral tissues arise from circulating progenitors, and recent mouse studies suggest distinctions between the origins of neonatal MCs and adult MCs. However, little is known about human neonatal MC progenitors and how they differ from adults. Therefore, we wanted to use a novel approach to identify the cord blood (CB) MC progenitor that gives rise to the mature MC using a validated culture system.
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