Abstract
assessed by measuring serum cytokine levels. Method : Serum interleukin-1 beta(IL-1β), IL-2, IL-4, IL-6, IL-10, IL-12(p40), tumor necrosis factor-alpha(TNF-α), interferon-gamma(IFN-γ) and transforming growth factor-beta(TGF-β) levels were measured in 83 patients with pulmonary tuberculosis, 10 patients with endobronchial tuberculosis before treatment and 20 healthy subjects by using a sandwich ELISA. In patients with pulmonary tuberculosis, they were divided into mild, moderate and far advanced group according to the severity by ATS guidelines. To compare with those of pretreatment levels, we measured serum IL-1β, IL-2, IL-4, IL-6, IL-10, IL-12(p40), TNF-α, IFN-γ and TGF-β levels in 45 of 83 patients with pulmonary tuberculosis after 2 and 6 months of treatment.
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