Abstract
Copoly(β-stearyl l-aspartate-β-benzyl l-aspartate)s (copoly(SLAsp-BLAsp)s) with various compositions were synthesized by ester exchange reaction of parent poly(β-benzyl l-aspartate) (PBLAsp). Circular dichroism (c.d.) studies were performed in chloroform solutions and for solid films as a function of degree of stearylation and temperature. The left-handed α helix of copoly(SLAsp-BLAsp) transformed to right-handed with increasing degree of stearylation at room temperature. A temperature-induced reversal of α helix sense from right to left was observed in chloroform solution of copoly(SLAsp-BLAsp) of certain composition, e.g. degree of stearylation 41 and 63%. On the other hand, two kinds of conformational behaviour were observed in solid films with respect to composition. At low degree of stearylation (0–30%), and α–ω transition occurred, while at degree higher than 40%, the α helix sense reversed from right-handed to left-handed as the temperature increased. All the conformational behaviours observed in solid films were irreversible, but they were reversible in solution.
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