Abstract
Seventeen patients suffering from chronic fatigue syndrome have been studied twice for at least 24 h, once at home and again in the hospital. On both occasions, a diary of sleep and different types of activity was kept, and rectal temperature was measured regularly. The circadian rhythm of temperature was assessed by cosinor analysis both before (raw data) and after “purification” to reveal the endogenous component of the rhythm. Results indicated that there were changes in the amplitudes and acrophases of the temperature rhythm that could be attributed to differences in masking caused by the sleep/activity cycles in the two environments. Some implications of these findings for the choice of “control subjects,” for the analysis of causes of alterations in circadian rhythms in aged and depressed patients, and for some current forms of treatment of such patients are considered.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
