Abstract
Concentrations of blood norepinephrine, serotonin and corticosterone, glucose, liver glycogen, and regional brain norepinephrine were measured during a 24 h period in F 1 hybrid rabbits of lines III × III c. Significant diurnal variations in brain norepinephrine occurred in frontal cortex and hypothalamus, but not in the amygdala. There was a minor correlation between brain and systemic norepinephrine concentrations, but further work is necessary to clarify the exact relationship. Generally, it appears that 2 p.m. is the time when most measurements exhibit least activity, while 7 p.m. appears to be the onset of increased activity.
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