Abstract
Summary The effectiveness of treating human brucellosis caused by Brucella melitensis with a 6-week course of ciprofloxacin plus doxycycline, versus rifampicin plus doxycycline was analysed by a prospective study of 24 patients. Subjects with central nervous system involvement, endocarditis, or spondylitis were not included in this study. All patients completed the full treatment and became afebrile in 5 days of therapy. Two patients (one in cach group) suffered relapses during the follow-up period. We conclude that the combination ciprofloxacin and doxycycline versus rifampicin and docycycline, is an effective treatment for the types of brucellosis included in this study, and they haven't any difference between these two therapeutic combinations.
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