Abstract
Spleen cells from C3H/HeN mice treated with BCG or Mycobacterium smegmatis displayed similar increased antibody-dependent cellular cytotoxicity (ADCC) in vitro. This activity, which increased between the tenth and the thirty-first day after stimulation, reached twice the amount of ADCC activity developed by the control spleen cells. C3H/HeN mice treated with a complete adjuvant including M. smegmatis and squalane displayed a lower increase in their ADCC capacity (30% instead of 100%). Les cellules spléniques de souris C3H/HeN traitées par Mycobacterium smegmatis selon différents protocoles ont une activité ADCC (CCDA) (cytotoxicité anticorps-dépendante à médiation cellulaire) accure envers des globules rouges de poussin, selon une cinétique identique et dans des proportions semblables à celles observées au cours d'un traitement par le BCG. Ces résultats peuvent être rapprochés de l'effet antitumoral exercé in vivo par ces deux immunostimulants.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
