Abstract
ObjectiveTo assess the efficacy and safety of cinnarizine for the prophylaxis of migraine associated vertigo in the vestibular migraine and migraine with brainstem aura.BackgroundVestibular migraine and migraine with brainstem aura are two principal clinical syndromes that frequently are associated with vertigo. Since cinnarizine is a well-tolerated calcium channel blocker which has acceptable effect on both vertigo and migraine headache, we carried out this study to evaluate the efficacy and safety of this medication in vestibular migraine and also migraine with brainstem aura associated with vertigo.MethodsThis was a retrospective, single-center, open-label, investigation of the effects of cinnarizine on vestibular migraine and migraine with associated with vertigo. We assessed the change in monthly frequency of vertigo and also frequency, duration and intensity of migraine attacks after one, two and three months of cinnarizine administration.ResultsThe mean frequency of vertigo and also the mean frequency, duration and intensity of migraine headaches per month were reduced significantly after three months of cinnarizine therapy (all p < 0.001).ConclusionThis study suggests that cinnarizine is safe and effective in reducing both headache and vertigo aspects of “migraine plus vertigo” among the patients who suffer from either vestibular migraine or migraine with brainstem aura associated with vertigo.
Highlights
Vestibular migraine and migraine with brainstem aura are two principal clinical syndromes that frequently are associated with vertigo
This study suggests that cinnarizine is safe and effective in reducing both headache and vertigo aspects of “migraine plus vertigo” among the patients who suffer from either vestibular migraine or migraine with brainstem aura associated with vertigo
Vestibular migraine (VM) and migraine with brainstem aura (BM) are two principal clinical syndromes that are associated with vertigo (Neuhauser 2009; Brandt 2004)
Summary
Vestibular migraine and migraine with brainstem aura are two principal clinical syndromes that frequently are associated with vertigo. Vestibular migraine (VM) (or migrainous vertigo) and migraine with brainstem aura (BM) (previously known as basilar-type migraine) are two principal clinical syndromes that are associated with vertigo (Neuhauser 2009; Brandt 2004). IHS requires an aura with two or more brainstem aura symptoms in addition to visual, sensory or dysphasic aura symptoms to qualify as BM criteria. These variants should be considered as two different migraine types (Society HCCotIH 2013)
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
