Abstract
Ciliated hepatic foregut cyst (CHFC) is a rare lesion which originates from detached hepatic diverticulum or from detachment and migration of buds from the esophageal and bronchial regions of the foregut which subsequently get entrapped by the liver during the early embryonic development of the foregut. CHFCs are mostly seen in adults and are rarely reported in children, with only about 10 cases reported in this age group. Hereby, we present two cases of CHFC in two 3.5-year-old boys; one of them had cystic lesion at medial segment of left lobe of liver (common site), and in the other one it was located at right lobe of liver (less common site). Histologically, both cysts had four layers composed of inner ciliated, pseudostratified, columnar epithelium; subepithelial connective tissue; smooth muscle layer; and an outer fibrous layer.
Highlights
Ciliated hepatic foregut cyst (CHFC), a rare foregut developmental malformation, usually presents as a solitary, unilocular, or occasionally multilocular cyst in the liver [1,2,3,4,5,6,7,8,9]
Histological features with a four-layered cyst wall, which consists of an inner ciliated, pseudostratified, columnar epithelium followed by subepithelial connective tissue, smooth muscle layer, and an outer layer fibrous tissue [1, 2, 4,5,6,7, 9, 10, 12, 15, 19], are characteristic of this lesion
One of the uncommon types of liver cyst is CHFC, which arises from the embryonic foregut
Summary
Ciliated hepatic foregut cyst (CHFC), a rare foregut developmental malformation, usually presents as a solitary, unilocular, or occasionally multilocular cyst in the liver [1,2,3,4,5,6,7,8,9]. This congenital lesion is rare and is mostly diagnosed in adults, with estimated 100 cases reported in the world literature, many of them in Japan [1,2,3, 6,7,8, 10,11,12]. These are the first pediatric cases to be reported from Iran
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