Abstract
ObjectiveCigarette smoking had been confirmed as an increased risk for dyslipidemia, but none of the evidence was from long-lived population. In present study, we detected relationship between cigarette smoking habits and serum lipid/lipoprotein (serum Triglyceride (TG), Total cholesterol (TC), Low-density lipoprotein (LDL) and high-density lipoprotein (HDL)) among Chinese Nonagenarians/Centenarian.MethodsThe present study analyzed data from the survey that was conducted on all residents aged 90 years or more in a district, there were 2,311,709 inhabitants in 2005. Unpaired Student’s t test, χ2 test, and multiple logistic regression were used to analyze datas.ResultsThe individuals included in the statistical analysis were 216 men and 445 women. Current smokers had lower level of TC (4.05 ± 0.81 vs. 4.21 ± 0.87, t = 2.403, P = 0.017) and lower prevalence of hypercholesteremia (9.62% vs. 15.13%, χ2 = 3.018,P = 0.049) than nonsmokers. Unadjusted and adjusted multiple logistic regressions showed that cigarette smoking was not associated with risk for abnormal serum lipid/lipoprotein.ConclusionsIn summary, we found that among Chinese nonagenarians/centenarians, cigarette smoking habits were not associated with increased risk for dyslipidemia, which was different from the association of smoking habits with dyslipidemia in general population.
Highlights
Dyslipidemia was the presence of abnormal levels of lipids in the blood, characterized by an elevation of the concentration of total cholesterol (TC), low-density lipoprotein (LDL), and triglycerides (TG), and a decrease in highdensity lipoprotein cholesterol (HDL) [1,2]
In the present study, using data from a sample of Chinese nonagenarians and centenarians, we examined the association between hypertension and dyslipidemia in the long-lived subjects
Current smokers had a lower TC serum level and a lower a prevalence of abnormal TC than nonsmokers, but no difference in the other serum lipid/lipoprotein levels and the prevalence abnormal of those We examined the difference of serum Lipid/Lipoprotein and prevalence of abnormal serum Lipid/Lipoprotein between smokers and nonsmokers
Summary
Dyslipidemia was the presence of abnormal levels of lipids in the blood, characterized by an elevation of the concentration of total cholesterol (TC), low-density lipoprotein (LDL), and triglycerides (TG), and a decrease in highdensity lipoprotein cholesterol (HDL) [1,2]. A comprehensive meta-analysis by Craig et al examined published data from 1966 to 1987 and estimated the excess risk posed by smoking on CVD, with particular emphasis on lipid and lipoprotein involvement [1]. Results of their analysis indicated that compared with non-smokers, cigarettes smokers had significantly higher TC (3%), TG (9.1%), and LDL (10.4%), higher (but not significant LDL (1.7%), and lower concentrations of HDL (−5.7%) [1]. They reported dose related decreases in HDL (0, −4.6, −6.3, −8.9%) [1]
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