Abstract
In women, the number and quality of oocytes, as well as the gradual decrease in both of these parameters with age, largely determines reproductive potential. The decrease in oocyte quality is thought to be due to errors in chromosome segregation during meiosis I, and the frequency of these errors increases with advancing maternal age. Chromosome mis-segregation in oocytes also leads to miscarriage and birth defects, yet the basis of these errors is poorly understood. While the incidence of chromosomal abnormalities and thus, birth defects, increases with age, there is currently no feasible or effective way to delay ovarian aging or improve oocyte quality.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
