Abstract
There are few reports on chronological pulmonary function test results in children who have experienced near-fatal status asthmaticus. To further investigate this point, we studied periodically the pulmonary function tests in 92 children with bronchial asthma (61 males and 31 females) who had been hospitalized for more than one month. Subjects were divided into two groups. Intubation (+) group; patients who required intubation for severe attacks (four males and three females). Intubation (-) group; patients who never experienced intubation (57 males and 28 females). It was significant that FEV1.0%, %FE V1.0, %MMF, %V50, and %V25 were lower in intubation (+) group than intubation (-) group, FEV1.0% was negatively correlated with the morbid period (r=-0.814, p<0.05) in intubation (+) group, Three patients were intubated in hospitalized, and they had persisted airway-obstruction, which appeared to be related to the number of intubation episode. From the results, it is suggested that patients in intubation (+) group have narrowing of small airways even when they do not have an asthmatic attack, and the more morbid period is extended, the more airway-obstruction may progress.
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Schedule a callMore From: Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology
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