Abstract

The aim of the present study was to determine the correlation between chronological age and biological age by characterizing age-specific serum anti-Müllerian hormone (AMH) values for 3280 Chinese women. A retrospective analysis including 3280 females between 10 to 52 years old was conducted from January 2016 to December 2016 in the clinical laboratory of Center for Reproductive Medicine, The Third Affiliated Hospital of Sun Yat-sen University, China. All included women were divided into several groups by age. Distribution and Statistical description of age-specific AMH levels was provided. Our results showed that serum AMH levels were negatively correlated with age (r = −0.606, p < .001). AMH concentrations approximately 31.1% depended on age and descended by an average of 6.2% per year. Around 25, 35 and 40 years, the decrease of AMH values accelerated. In conclusion, biological age was inversely correlated with chronological age. The present data can provide information for evaluating the fertility potential and ovarian reserve of infertile patients, as well as facilitate clinicians to decide individual treatment options.

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