Abstract

Down syndrome is a chromosomal abnormality (trisomy 21) characterized by an extra chromosome 21. People with Down syndrome have impairement in mental and physical development, including delayed dental development. Dental age is stage of development of teeth measured by maturation stage of teeth. This study aims to determine or asses the growth or maturation of permanent teeth in children with Down syndrome. This research was a cross-sectional analysis. Analysis test using paired t-test to compare the average of chronological age to dental age, also unpaired t-test for comparing the dental age of children with Down syndrome to normal based on chronological age. The result showed that there was significant difference between chronological age and dental age in children with Down syndrome (p-value 0,05). The conclusion of this study showed that dental age more late than chronological age in children with Down syndrome. In spite dental age in Down syndrome children is descriptively later than in normal.

Highlights

  • Down Syndrome is a chromosomal disorder (Trisomy 21) in children and mostly revealed/found out in dental clinics

  • Analysis were done on Down Syndrome (DS) children to collect the dental age score to be compared with chronological age

  • The rate in chronological age is 8.97 years and 7.91 years in dental age, that means dental age in DS children is delayed 1 year 1 month compared to chronological age

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Summary

Introduction

Down Syndrome is a chromosomal disorder (Trisomy 21) in children and mostly revealed/found out in dental clinics. A person with Down Syndrome has an extra chromosome, namely chromosome 21. This extra chromosome will change the body genetical balance that might cause a change in physical characteristic and intellectual ability beside disorders of physiological function of the body. The syndrome is a genetical anomaly caused by numeric aberation as a failure of replication process and nondisjunction of the cell (Hidajat et al, 2005; Rinaya, 2003; Moraes et al, 2007a). As results of chromosomal disorders, patients with Down Syndrome (DS) have disorders of mental and physical development including delayed dental development (Sjarif, 2011)

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