Chronobiological evaluation and an intervention study on timing of food intake in the treatment of obesity.

Abstract

The chronotype of patients who cannot reach their ideal weight despite diet and exercise may play a role in this resistance. In this study, the relationship between BMI and chronobiological preferences was examined and a weight loss programme was applied to refractory obese patients with evening type (ET). The study included 50 obese (BMI≥30kg/m2 ), 50 overweight (BMI=25-29kg/m2 ) and 50 normal weight (BMI<25kg/m2 ). The patients were asked to fill out a questionnaire including questions about sociodemographic characteristics, breakfast and night eating habits, as well as the morningness-eveningness quastionnaire (MEQ). In the second stage of the study, awareness interviews were held with ET obese patients in terms of eating time and habits. A statistically significant difference was observed between the BMI averages and the MEQ scores of ET, intermediate type (IT) and morning type (MT) groups (P=.0001). There was a statistically significant difference between the ET, IT and MT groups in terms of the distribution of late-night eating habits (P=.0001). The habit of skipping breakfast and taking more calories at dinner was found to be high in the ET patients (respectively; P=.021, P<.001). According to the results of the 3-month follow-up and intervention, the ET patients lost an average of 9.07±4.30 kg and a significant decrease was observed in the BMI scores (P<.001). The study results support the idea that an individualised weight loss programme according to the patient's chronotype preferences may increase the success rate of obesity treatment. A weight loss programme that includes the timing of food intake and regulation of eating habits in evening-type obese patients can be used in the treatment of obesity.