Chrono-medical impact on morning hypertension therapy and home blood pressure measurement: The Val-HOPE study

Abstract

We evaluated chrono-medically the effect of valsartan's therapy on home-measured blood pressure (BP) in patients, whose blood pressure was inadequately controlled with or without anti-hypertensive agents. The subjects were 42 men and 63 women, of average age of 63.4years. Administration of valsartan significantly reduced blood pressure both at the clinic and at home, i.e., from 158.6±13.7/90.9±11.6 to 139.3±12.9/82.5±10.2mmHg, and from 150.0±11.6/89.4±10.9 to 136.6±11.9/82.5±10.2mmHg (p<0.001), respectively.