Abstract
New Coccine and Nigrosine, at levels of 0·03, 0·3 and 3·0 per cent in the diet, had no effect on mortality in male or female rats. In groups receiving Malachite Green at levels of 0·3 and 3·0 per cent in the diet there was 100 per cent mortality within the first week of the experiment. Female rats receiving Malachite Green at 0·03 per cent or Nigrosine at 3·0 per cent in the diet showed a significant decrease in growth rate. For the group on Malachite Green this was accompanied by a decrease in food consumption. In both male and female rats receiving Nigrosine at 3·0 per cent in the diet, there was an increase in the organ-body weight ratio for liver and kidneys. Histopathological changes attributed to the toxic effects of the colours were noted in kidneys and testes.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
