Abstract

In the great majority of cases, halitosis is originated in the mouth itself and psychological symptoms have been pointed out as one of halitosis‐inducing factor. The aim of this study was to evaluate, in laboratory animals, the effect of chronic mild stress (CMS) on the production of volatile sulfur compounds (VSC), the main component of bad breath. VSC measurements were made using a portable industrial monitor (Halimeter) once a week, during seven weeks, in control and stressed adult males Wistar rats. CMS group was submitted to the stress protocol on weeks 3, 4 and 5 (Student t test; p<0.05). Rats submitted to CMS presented an increase in the production of oral VSC, in comparison to the control group, on week 3 (22±1 vs. 18±1 ppb), week 4 (25±1 vs. 16±1 ppb), week 5 (24±1 vs. 17±1 ppb) and week 6 (26±2 vs.19±1 ppb), with no difference on week 7 (16±1 vs. 16 ± 0.6 ppb). Our data confirm the influence of stress on the production of oral VSC and demonstrate that this effect is still observed one week after the cessation of stress stimulus. Financial Support: FAPESP, CNPq

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