Abstract

A review of the literature indicates that the clinicopathologic picture of sclerosing non-suppurative osteomyelitis has been generally misunderstood. Not only has there been lack of unanimity in the proper interpretation of this osseous lesion, but there has been actual distortion of the features which Garre (1, 2) defined under this heading. Essentially, sclerosing osteomyelitis of Garre, according to the translation by Jaffe and Lichtenstein (3) of Garree's original article (1), in which he described the “sclerosing non-suppurative form” as one among a variety of expressions of acute osteomyelitis, includes “… those infectious osteomyelitides which leave behind merely a distention and thickening of the bone, without leading to the development of suppuration and fistula formation. They set in in typical fashion quite acutely, at least in the majority of cases, and run their course with high fever, swelling of the extremity, painfulness and distention of the bones, and indeed even with considerable infilt...

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