Abstract

We describe the technological development of a web platform named CHRONIC-PHARMA that integrates three prescription support tools for patients with chronic diseases: Anticholinergic Burden Calculator (ABC), LESS-CHRON criteria and TRIGGER-CHRON. They focus on the optimization and evaluation of pharmacotherapy in patients with chronic diseases, resulting in a useful, single platform that can facilitate the review of pharmacotherapy and improve the safety of chronically ill patients. This is achieved by estimating and reducing the anticholinergic risk (ABC), detecting opportunities for deprescribing drugs and monitoring its success (LESS-CHRON criteria), as well as calculating the risk of adverse drug events (TRIGGER-CHRON). The platform is freely accessible online (https://chronic-pharma.com/) as well as through a mobile application, and therefore easily accessible among the healthcare community.

Highlights

  • The high prevalence of chronic diseases is changing the profile of patients who require healthcare

  • The objective of this work is to describe the technological development of a platform that integrates the three tools developed by our research group: the Anticholinergic Burden Calculator (ABC) Calculator, the LESS-CHRON Criteria and the TRIGGER-CHRON criteria

  • It has integrated three tools that can be used independently in each registered patient: estimating the anticholinergic risk and assessing possible interventions for its reduction (ABC), detecting drugs to be deprescribed and monitoring its success (LESS-CHRON) and calculating the risk that a patient has of having an adverse drug events (ADEs) (TRIGGER-CHRON). (Fig. 2)

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Summary

Introduction

The high prevalence of chronic diseases is changing the profile of patients who require healthcare. Implementing an appropriate treatment plan for these patients is a difficult and complex process. They require a comprehensive quality approach, with appropriate pharmacotherapeutic optimization mediated by prescription support tools which standardize the. There are widely accepted tools that have been consolidated as guidelines to help in the global review of treatment in elderly patients: STOPP-START criteria or the Beers criteria [2, 3]. They are fundamental tools to be considered in any digital platform for the global review of treatment in elderly patients. A computer-generated STOPP/ START is currently being investigated to examine the impact of criteria on incident ADRs (SENATOR) and drug-related hospitalizations (OPERAM) [4]

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