Abstract
The pancreas is an organ that plays a key role in the digestive process, preparing food ingredients such as proteins, fats and carbohydrates for adequate absorption in the small intestine. Today, a wide range of pathological conditions is known in which the tissue of the pancreas is affected and its functions are lost. The literature review examined various diseases that phenotypically manifest as pancreatitis, as well as various diagnostic and therapeutic strategies.
Highlights
С наибольшей частотой у пациентов встречались мутации в гене CFTR (38%), затем – SPINK1 (25%), CTRC (7%) и PRSS1 (4%)
Ряд авторов [10,32], утверждают, что 20%-40% детей с рецидивирующим панкреатитом в течение 5 лет от начала заболевания прогрессируют до хронического
R Perito, Tonya M Palermo, John F Pohl, Maria Mascarenhas, Maisam Abu-El-Haija et al, Factors Associated With Frequent Opioid Use in Children With Acute Recurrent and Chronic Pancreatitis, J Pediatr Gastroenterol Nutr
Summary
The pancreas is an organ that plays a key role in the digestive process, preparing food ingredients such as proteins, fats and carbohydrates for adequate absorption in the small intestine. A wide range of pathological conditions is known in which the tissue of the pancreas is affected and its functions are lost. The literature review examined various diseases that phenotypically manifest as pancreatitis, as well as various diagnostic and therapeutic strategies. Хронические панкреатиты у детей: между гастроэнтерологом и хирургом | Chronic pancreatitis in children: between gastroenterologist and surgeon. Поражения поджелудочной железы обусловливаются широчайшим спектром патогенных факторов, что может привести к необратимым изменениям в тканях органа, утрате функций и последующей гибели организма. Что деятельность поджелудочной железы может быть нарушена вследствие различных причин, то и под термином «панкреатит» может пониматься гетерогенная группа заболеваний, требующая различных диагностических и терапевтических стратегий
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