Abstract
Chronic lymphoproliferative disorders represent a group of malignant lymphoid diseases of whom chronic lymphoid leukaemia (CLL) is the more frequent. They are incurable diseases of indolent evolution. Diagnosis is usually made on blood puncture when circulating malignant lymphocytes are present. Explorations are limited to CT-scan, and, for CLL, karyotype. Bone marrow biopsy must be avoided, as possible. Treatment indications will be limited to really evolved cases. The aim of treatment must be the quality of life. Adapted treatment are available for the majority of patients, with limited toxicity and prolonged efficacy.
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