Abstract

Both chronic myeloid leukaemia (CML) and chronic lymphocytic leukaemia (CLL) are rare illnesses.Their co-existence has been previously reported, typically with CML following CLL. We report to ourknowledge the first case of CLL developing some years after initial diagnosis of Philadelphia (Ph)chromosome positive CML.We provide molecular evidence that CLL arose in a Ph negative clone. Theimplications of the findings are discussed.

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