Chronic lymphatic leukemia and multiple myeloma in the same patient.

Abstract

Case Reports1 November 1960CHRONIC LYMPHATIC LEUKEMIA AND MULTIPLE MYELOMA IN THE SAME PATIENTJOHN B. VANDER, M.D., HORTON A. JOHNSON, M.D.JOHN B. VANDER, M.D.Search for more papers by this author, HORTON A. JOHNSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-53-5-1052 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe close relationship which seems to exist between lymphocytes and plasma cells has recently been the subject of much discussion.1, 2 The frequent occurrence of apparently identical serum protein abnormalities in patients with malignant lymphoma, lymphatic leukemia and multiple myeloma, as demonstrated by paper electrophoresis, has been felt to be of particular significance. The consensus seems to be that plasma cells probably represent transitional forms of lymphocytes, as had been suggested by the work of Sundberg3 and others,4 and that both are capable of synthesizing abnormal serum proteins.Although serum proteins of the myeloma type have occasionally been reported in...Bibliography1. AzarHillOsserman HAWTEF: Malignant lymphoma and lymphatic leukemia associated with myeloma-type serum proteins, Am. J. Med. 23: 239, 1957. CrossrefMedlineGoogle Scholar2. : Multiple myeloma, current clinical and chemical concepts, Am. J. Med. 23: 283, 1957. MedlineGoogle Scholar3. Sundberg RD: Lymphocytes and plasma cells, Ann. New York Acad. Sc. 59: 671, 1955. CrossrefMedlineGoogle Scholar4. Kass EH: Occurrence of normal serum gamma globulin in human lymphocytes, Science 101: 334, 1945. CrossrefGoogle Scholar5. MoertelHagedom CGAB: Leukemia or lymphoma and coexistent primary malignant lesions. A review of literature and a study of 120 cases, Blood 12: 788, 1957. CrossrefMedlineGoogle Scholar6. Wall RL: The use of serum protein electrophoresis in clinical medicine, Arch. Int. Med. 102: 618, 1958. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication April 9, 1959.From the Pondville Hospital, Walpole, Massachusetts, and the National Cancer Institute, U. S. Public Health Service.†National Cancer Institute.‡Formerly, Department of Pathology, Pondville Hospital, Walpole, Massachusetts.Requests for reprints should be addressed to John B. Vander, M.D., Pondville Hospital, Walpole, Massachusetts. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDiagnostic and Clinical Considerations in Concomitant Bone Marrow Involvement by Plasma Cell Myeloma and Chronic Lymphocytic Leukemia/Monoclonal B-Cell Lymphocytosis: A Series of 15 Cases and Review of LiteratureThe association of chronic lymphocytic leukaemia and multiple myeloma: a study of eleven patientsTransformation of chronic lymphocytic leukemia to plasmacytomaMultiple Myeloma, Waldenström's Macroglobulinemia, and Benign Monoclonal Gammopathy: Characteristics of The B Cell Clone, Immunoregulatory Cell Populations and Clinical ImplicationsPlasma Cell Neoplasms and Acute LeukaemiaSimultaneous Occurrence of Clinical Manifestations of Myeloma and Waldenström's Macroglobulinemia with Monoclonal IgG Lambda and IgM Kappa in a Single PatientLymphoplasmacytic myeloma. An immunological, immunohistochemical and electron microscopic studyChronic Lymphocytic Leukaemia with Subsequent Development of Multiple MyelomaMultiple myeloma terminating in lymphocytic leukemia with B-lymphocyte membrane markersGaucher's disease associated with chronic lymphocytic leukaemia, gout and carcinomaMultiple myeloma terminating in acute leukemiaUnusual Cases of MyelomatosisParaproteinämische HämoblastosenKoinzidenz von familiär gehäuft auftretendem Plasmozytom, chronischer lymphatischer Leukämie und RektumkarzinomCombined Multiple Myeloma and Chronic Lymphatic LeukemiaStem Cell Leukaemia in MyelomatosisA Unique lymphoproliferative disorder associated with an IgM platelet agglutinin, diffuse hypergammaglobulinemia, amyloid deposition and excessive urinary excretion of IgG fragmentsDie paraproteinämischen HämoblastosenMultiple Primary Malignant Neoplasms of Different Tissues or OrgansZur Klassifizierung atypischer paraproteinämischer HämoblastosenCase 18-1961 1 November 1960Volume 53, Issue 5Page: 1052-1059KeywordsLesionsLymphocytesMultiple myelomaMyelomaPlasma cellsPneumoniaProteinsSerum proteinsSpineThorax Issue Published: 1 November 1960 PDF downloadLoading ...