CHRONIC LIVER DISEASE

Abstract

Objectives: To determine the frequency of non variceal upper gastrointestinalbleeding in the patients of chronic liver disease. Study Design: Cross sectional study. Placeand Duration of Study: All medical wards of Civil Hospital and Ojha campus, Dow Universityof Health Sciences, Karachi, Pakistan from May 2013 to January 2015. Methodology: A total of267 patients of chronic liver disease (CLD) who presented with upper GI bleed (hematemesis ormelena) were included in this study. Before the endoscopic procedures, patients were clinicallyevaluated by gastroenterology fellows at the time of patient’s presentation. Upper GI endoscopywas performed within 48 hours in all hemodynamically stable patients. Results: The averageage of the patients was 44.27±12.13 years. Frequency of non variceal upper gastrointestinalbleeding (NVUGIB) in the patients of chronic liver disease was 56.93% (152/167). Conclusion:It is concluded that current magnitude of NVUGIB is very high in cirrhotic patients thereforeadequate planning and knowledge of the specific mechanisms explaining the prognosticfactors of NVUGIB to prevent it and thereby reducing the morbidity and mortality in ChronicLiver Disease.