Abstract
A woman with melanoderma, with a previous histopathological diagnosis of squamous cell carcinoma in the hard palate central region, reported to not smoking or consuming alcohol during anamnesis. The intrabuccal examination revealed an exophytic lesion, 1 cm in its largest diameter, irregular, showing purplish coloration, painless, and unmodified since the beginning of the diagnostic process. Laboratory tests were negative for HIV, HPV, tuberculosis, and syphilis. Before proceeding for definitive oncological treatment, the histological slides from the initial biopsy were reviewed by an oral pathologist. The result of this histopathological analysis indicated pseudocarcinomatous hyperplasia with associated lymphocytic infiltrate. Thus, another partial biopsy was performed, aimed at a definitive diagnosis with the immunohistochemical analysis; the results were negative for CD10 and Cyclin D1, and positive for CD20, CD3, Ki-67, and anti-apoptotic protein Bcl-2. The result, chronic lichenoid inflammatory process with hyperplasia was established. Periodic clinical follow-up was the proposed therapeutics.
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