Abstract
Reflux of gastric contents to the level of the pharynx and larynx is called laryngopharyngeal reflux, which can exist as such or laryngeal and pharyngeal reflux as separate entities, and in such form may lead to other diseases such as rhinitis, sinusitis, otitis media, and precancerous cancerous condition. To determine the relationship and impact of gastroesophageal reflux disease on the occurrence, frequency and duration of inflammatory processes and mucosal damage to the larynx. All patients were obtained anamnesticly, lab test done in all patients, indirect hipofaringo and laryngoscopy was performed in all patients. Based on the feedback reports gastroenterologists, we obtained data of gastroscopy. Results: 120 subjects were processed with dyspeptic symptoms. Based on history, all patients had some symptoms of upper respiratory tract disease.62 (51.66%) male respondents and 58 (48.33%) females. The average age of 54 years. In 82 (68.33%) patients was increased salivation (one of the leading symptoms), of that number in 61 (74.39%) participants laryngitis was present. In 68 (56.66%) cases where the predominant symptom was cough, laryngitis was present in 26 (38.23%). In 70 (58.33%) of patients with globus sensation, laryngitis was present in 38 (54.28%) patients. Smoking has been represented with 65.83% (70) respondents, the percentage of patients with chronic laryngitis in this group was 69.62% (55) respondents. Been held after gastroscopy and otorinolaryngological examination in 62 (51.66%) patients were diagnosed gastroesophageal reflux disease (GERD), of which, in 43 (69.35%) patients laryngitis was present. After a three-month follow-up of patients with therapy (H2 blockers, proton pump inhibitors and antacids) 28 (65.11%) subjects (total treated), showed an improvement. The results of this study indicate a significant correlation between gastroesophageal reflux disease and chronic laryngitis, as well as the favorable impact and effect of antacid therapy in the treatment of laryngitis.
Highlights
Trajković R.1, Trajkovic B.2, Todorovic D.2, Đokić N.2, Inić Kostić B.2 1 Medicinski fakultet Priština, Kosovska Mitrovica, Srbija 2 Dom Zdravlja Gračanica, Gračanica, Srbija
Ova pojava se često ne prepoznaje zato što samo trećina osoba kod kojih se kiselina podiže u ždrelo ima specificne simptome a jako je vazno naglasiti da čak 70% pacijenata nema nikakvih problema sa želucem, a ima tegobe od kojih posebno ističemo uporan kašalj, knedlu u grlu, slivanje sekreta, čestu promuklost kao i probleme sa glasom profesionalnih pevača
The results of this study indicate a significant correlation between gastroesophageal reflux disease and chronic laryngitis, as well as the favorable impact and effect of antacid therapy in the treatment of laryngitis
Summary
Trajković R.1, Trajkovic B.2, Todorovic D.2, Đokić N.2, Inić Kostić B.2 1 Medicinski fakultet Priština, Kosovska Mitrovica, Srbija 2 Dom Zdravlja Gračanica, Gračanica, Srbija. Refluks želudačnog sadržaja do nivoa ždrela i larinksa naziva se laringofaringealni refluks, koji može postojati kao takav ili laringealni i faringealni refluks kao posebni entiteti, i kao takvi dovesti do drugih oboljenja kao što su rhinitis, sinusitis, otitis media, prekanceroznih i kanceroznih stanja. Kod ukupnog broja pacijenata sa globus senzacijama 70 (58,33%), laringitis je bio prisutan u 38 (54,28%) ispitanika. Brojnim studijama je pokušavano da se nađe uzročno posledična veza između gastroezofagusne refluksne bolesti (GERD) i velikog broja bolesti gornjih disajnih puteva kao što su: laringaealni malignitet, astma, hronični kašalj, rinitis, sinusitis, otitis media itd. Refluks želudačnog sadržaja do nivoa ždrela (pharinx) i larinksa naziva se laringofaringealni refluks, koji može postojati kao takav ili laringealni i faringealni refluks kao posebni entiteti, i kao takvi dovesti do drugih oboljenja kao što su rhinitis, sinusitis, otitis media itd. Rasvetljavanje uloge laringofaringealnog refluksa u patogenezi navedenih bolesti moglo bi promeniti dosadasnje prevencijske i terapijske postupke
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