Chronic Kidney Disease and Major Risk Factors in Patients from Two Large Healthcare Systems: The CURE-CKD Registry

Katherine Tuttle,Keith C Norris,Kenn B Daratha,Joshua J Neumiller,Douglas S Bell,Radica Z Alicic,Sterling M Mcpherson,Susanne B Nicholas,O Kenrik Duru,Cami R Jones,Carol M Mangione

doi:10.2139/ssrn.3411052

Abstract

Author(s): Tuttle, Katherine; Alicic, Radica Z; Duru, O Kenrik; Jones, Cami R; Daratha, Kenn B; Nicholas, Susanne B; McPherson, Sterling M; Neumiller, Joshua J; Bell, Douglas S; Mangione, Carol M; Norris, Keith C

Highlights

Diabetes is the leading cause of Chronic kidney disease (CKD) and a global health emergency, with 425 million individuals affected worldwide in 2017 and a projected 629 million individuals affected by 2045.8-10 Hypertension is the second most frequent cause of CKD, affecting nearly one-third of US adults and 1.13 billion people globally in 2015.11,12 The estimated population size for prediabetes was 78.5 million among adults in the United States between 2011 and 2014, and nearly one-tenth have been reported with CKD.13
Awareness of CKD and its major risk factors remains strikingly low among health care professionals and patients alike
We identified CKD categories 1 and 2 by an administrative code, urine albumin to creatinine ratio greater than 30 mg/g, and/or urine protein to creatinine ratio greater than 150 mg/g

Summary

Introduction

An estimated 1 in 7 to 10 adults worldwide have CKD, with only approximately 10% surviving to ESKD and only half of survivors receiving dialysis or a kidney transplant because of lack of access or high costs.. The increasing prevalence of CKD is closely tied to the increase of at-risk populations with diabetes, hypertension, and prediabetes. Diabetes is the leading cause of CKD and a global health emergency, with 425 million individuals affected worldwide in 2017 and a projected 629 million individuals affected by 2045.8-10 Hypertension is the second most frequent cause of CKD, affecting nearly one-third of US adults and 1.13 billion people globally in 2015.11,12 The estimated population size for prediabetes was 78.5 million among adults in the United States between 2011 and 2014, and nearly one-tenth have been reported with CKD.. Diabetes is the leading cause of CKD and a global health emergency, with 425 million individuals affected worldwide in 2017 and a projected 629 million individuals affected by 2045.8-10 Hypertension is the second most frequent cause of CKD, affecting nearly one-third of US adults and 1.13 billion people globally in 2015.11,12 The estimated population size for prediabetes was 78.5 million among adults in the United States between 2011 and 2014, and nearly one-tenth have been reported with CKD. Even so, awareness of CKD and its major risk factors remains strikingly low among health care professionals and patients alike.

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Discussion

Conclusion