Abstract
The study was registered as clinical trial #NCT01581125.
Highlights
Over 30% of Americans are obese [1] and 1.4 billion adults worldwide are overweight [2, 3]
We investigated how chronic insufficient sleep impacts the circadian timing of subjective hunger and fasting metabolic hormones in a 32-day in-laboratory randomized single-blind control study, with healthy younger participants randomized to either Control (1:2 sleep:wake ratio, 6.67 h sleep:13.33 h wake, n = 7, equivalent to 8 h of sleep per 24 h) or chronic sleep restriction (CSR, 1:3.3 sleep:wake ratio, 4.67 h sleep:15.33 h wake, n = 8, equivalent to 5.6 h of sleep per 24 h) conditions
Several studies have found that acute sleep restriction can lead to changes in appetitive hormones that would stimulate hunger: a decrease in the satiety hormone leptin [10, 18,19,20] and an increase in the appetitive hormone ghrelin [10, 19, 21, 22]
Summary
Over 30% of Americans are obese [1] and 1.4 billion adults worldwide are overweight [2, 3]. If food is provided ad libitum, participants during acute sleep restriction eat far more calories than needed to meet energy balance, despite increased leptin and decreased ghrelin concentrations [15, 16, 23], bringing the hormonal mechanism for increased food intake into question [24]. It is not well understood how the levels of these hormones will react to chronic exposure to sleep restriction, which is a common cause of sleep loss and may be more important for metabolic health, as appreciable weight gain occurs chronically [25]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
