Abstract
The implanted system was composed of four silver ball electrodes placed in the burr hole of the skull, a reference placed subcutaneously near the nose, two electrodes for EMG, and a ground. The dural attachment was 0.1 mm in diameter. A cassette connector was placed on the back. Implanted cables between the cassette connector and all electrodes consist of twisted fine wires placed in a silicone tube 0.5 mm in diameter. The implanted electrode system weighed 0.8 g. The outlet cables were of the same materials used for implanted cables and placed in a silicone tube 1.5 mm in diameter. The impedance matching between these cables was successful and assured the minimum contamination of artifacts in the EEG recording of freely moving mice. Long-term (4–5 weeks) recording, thus, became possible without damage to the implanted materials. Monopolar recordings demonstrated the localized paroxysmal discharges during general tonic clonic convulsion in El mice. Several artifacts are presented.
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